If you have racial expertise the mace wins. If you don't and are looking at 80 the axe, and for short gains the sword.
At 80 defense is not realistically an issue, between the saronite, rep rewards and old gear and trinkets (scarab and adamantite or the old quest reward one) 520 ish to start heroics is easy. The defense difference is maybe 1 point of defense, and the way avoidance stats are dropping avoidance is useful.
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Armoury Link
